Our Publications
Endocrine regulation function of the muscle-skeletal apparatus
Sansoni V, Vernillo G, Perego S, Barbuti A, Merati G, Schenza F, La Torre A, Banfi G, Lombardi G. Bone turnover response is linked to both acute and established metabolic changes in ultra-marathon runners. Endocrine 2017;56(1):196-204.
Lombardi G, Sanchis-Gomar F, Perego S, Sansoni V, Banfi G. Implications of exercise-induced adipo-myokines in bone metabolism. Endocrine 2016;54(2):284-305.
Corsetti R, Barassi A, Perego S, Sansoni V, Rossi A, Damele C, Melzi d’Eril GL, Banfi G, Lombardi G. Changes in urinary amino acids excretion in relationship with muscle activity markers over a professional cycling stage race: in search of fatigue markers. Amino Acids 2016;48(1):183-92.
Lombardi G, Perego S, Luzi L, Banfi G. A four-season molecule: osteocalcin. Updates in its physiological roles. Endocrine 2015;48(2):394-404.
Grasso D, Corsetti R, Lanteri P, Di Bernardo C, Colombini A, Graziani R, Banfi G, Lombardi G. Bone-muscle unit activity, salivary steroid hormones profile and physical effort over a 3-week stage race. Scand J Med Sci Sport 2015;25(1):70-80.
Lombardi G, Corsetti R, Lanteri P, Grasso D, Vianello E, Marazzi MG, Graziani R, Colombini A, Galliera E, Corsi Romanelli MM, Banfi G. Reciprocal regulation of calcium/phosphate-regulating hormones in cyclists during the Giro d’Italia 3-week stage race. Scand J Med Sci Sport 2014;24(5):779-87.
Lombardi G, Lanteri P, Graziani R, Colombini A, Banfi G, Corsetti R. Bone and energy metabolism parameters in professional cyclists during the Giro d’Italia 3-weeks stage race. PLoS ONE 2012;7(7):e42077.
Biomarkers of muscle and skeletal tissues
Perego S, Grasso D, Bodini BD, Cavaiani F, De Santis C, Ursino N, Pelosi C, Banfi G, Lombardi G. Perisurgical and intra-rehabilitative salivary steroid hormone profiles in bicompartmental arthroplasty. J Biol Regul Homeost Agents 2015;29(4):953-60.
Mora S, Puzzovio M, Giacomet V, Fabiano V, Maruca K, Capelli S, Nannini P, Lombardi G, Zuccotti GV. Sclerostin and DKK-1: two important regulators of bone metabolism in HIV-infected youths. Endocrine 2015;49(3):783-90.
Lombardi G, Lanteri P, Colombini A, Banfi G. Blood biochemical markers of bone turnover: pre-analytical and technical aspects of sample collection and handling. Clin Chem Lab Med 2012;50(5):771-89.
Lombardi G, Lanteri P, Colombini A, Mariotti M, Banfi G. Sclerostin concentrations in athletes: role of load and gender. J Biol Regul Homeost Agents 2012;26(1):157-63.
Banfi G, Colombini A, Lombardi G, Lubkowska A. Metabolic markers in sports medicine. Adv Clin Chem 2012;56:1-54.
Lombardi G, Colombini A, Freschi M, Tavana R, Banfi G. Seasonal variation of bone turnover markers in top-level female skiers. Eur J Appl Physiol 2011;111(3):433-40.
Banfi G, Lombardi G, Colombini A, Lippi G. Bone metabolism markers in sports medicine. Sports Med 2010;40(8):697-714.
Muscle-skeletal pathophysiology
Cauci S, Viganò M, De Luca P, Perucca Orfei C, Banfi G, Lombardi G, Brayda-Bruno M, Colombini A. High levels of circulating type II collagen degradation marker (CTx-II) are associated with specific VDR polymorphisms in patients with adult vertebral osteochondrosis. Int J Mol Sci 2017;18:2073.
Brayda-Bruno M, Viganò M, Cauci S, Vitale JA, de Girolamo L, De Luca P, Lombardi G, Banfi G, Colombini A. Plasma vitamin D and osteo-cartilaginous markers in Italian males affected by intervertebral disc degeneration: Focus on seasonal and pathological trend of type II collagen degradation. Clin Chim Acta 2017;471:87-93.
Xu J, Lombardi G, Jiao W, Banfi G. Effects of exercise on bone status in female subjects from young girls to postmenopausal women: an overview of systematic reviews and meta-analyses. Sports Med 2016;46(8):1165-82.
Colombini A, Brayda-Bruno M, Lombardi G, Croiset SJ, Ceriani C, Buligan C, Barbina M, Banfi G, Cauci S. BsmI, ApaI and TaqI polymorphisms in the vitamin D receptor gene (VDR) and association with lumbar spine pathologies. PLoS ONE 2016;11(5):e0155004.
Sansoni V, Perego S, Colombini A, Banfi G, Brayda-Bruno M, Lombardi G. Interplay between low plasma RANKL and VDR-FokI polymorphism in lumbar disc herniation independently from age, body mass, and environmental factors. A case-control study in the Italian population. Eur Spine J 2016;25:192-99.
Colombini A, Lopa S, Ceriani C, Lovati AB, Croiset SJ, Di Giancamillo A, Lombardi G, Banfi G, Moretti M. In vitro characterization and in vivo behavior of human nucleus pulposus and annulus fibrosus cells in clinical grade fibrin and collagen-enriched fibrin gels. Tissue Eng Part A 2015;21(3-4):793-802.
Colombini A, Brayda-Bruno M, Ferino L, Lombardi G, Maione V, Banfi G, Cauci S. Gender Differences in the VDR-FokI Polymorphism and conventional non-genetic risk factors in association with lumbar spine pathologies in an Italian case-control study. Int J Mol Sci 2015;16:3722-39.
Lombardi G, Grasso D, Berjano P, Banfi G, Lamartina C. Is minimally invasive spine surgery also minimally pro-inflammatory? Muscular markers, inflammatory parameters and cytokines to quantify the operative invasiveness assessment in spine fusion. Eur J Inflam 2014;12(2):237-49.
Colombini A, Brayda-Bruno M, Lombardi G, Croiset SJ, Vrech V, Maione V, Banfi G, Cauci S. FokI polymorphism in the vitamin D receptor gene (VDR) and its association with lumbar spine pathologies in the Italian population: a case-control study. PLoS ONE 2014;9(5):e97027.
Bettoni L, Bonomi FG, Zani V, Manisco L, Indelicato A, Lanteri P, Banfi G, Lombardi G. Effects of 15 consecutive cryotherapy sessions on the clinical output of fibromyalgic patients. Clin Rheumatol 2013;32(9):1337-45.
Colombini A, Cauci S, Lombardi G, Lanteri P, Croiset S, Brayda-Bruno M, Banfi G. Relationship between vitamin D receptor gene (VDR) polymorphisms, vitamin D status, osteoarthritis and intervertebral disc degeneration. J Steroid Biochem Mol Biol 2013;138C:24-40.
Colombini A, Lanteri P, Lombardi G, Grasso D, Recordati C, Lovi A, Banfi G, Bassani R, Brayda-Bruno M. Metabolic effects of vitamin D active metabolites in monolayer and micromass cultures of nucleus pulposus and annulus fibrosus cells isolated from human intervertebral disc. Int J Biochem Cell Biol 2012;44(6):1019-30.
Lombardi G, Acume MY, Colombini A, Moreau A, Banfi G. Biochemistry of adolescent idiopathic scoliosis. Adv Clin Chem 2011;54:165-82.
Colombini A, Lombardi G, Galliera E, Dogliotti G, Randelli P, Meerssemann A, Mineo G, Cabitza P, Corsi MM. Plasma and drainage fluid levels of soluble receptor activator of nuclear factor-κB (sRANK), soluble receptor activator of nuclear factor-κB ligand (sRANKL) and osteoprotegerin (OPG) during proximal humerus fracture healing. Int Orthop 2011;35(5):777-82.
Galliera E, Randelli P, Dogliotti G, Dozio E, Colombini A, Lombardi G, Cabitza P, Corsi MM. Matrix metalloproteases MMP-2 and MMP-9: are they early biomarkers of bone remodelling and healing after arthroscopic acromioplasty? Injury 2010;41(11):1204-7.
Colombini A, Lombardi G, Corsi MM, Banfi G. Pathophysiology of the human intervertebral disc. Int J Biochem Cell Biol 2008;40(5):837-42.
Exercise Physiology
Vitale JA, Lombardi G, Cavaleri L, Graziani R, Schoenuber H, La Torre A, Banfi G. Rates of insufficiency and deficiency of vitamin D levels in elite professional male and female skiers: A chronobiologic approach. Chronobiol Int [Epub Ahead of Print]
Lombardi G, Ziemann E, Banfi G. Whole-body cryotherapy in athletes: from therapy to stimulation. An updated review of the literature. Front Physiol 2017;8:258.
Lombardi G, Vitale JA, Logoluso S, Logoluso G, Cocco N, Cocco G, Cocco A, Banfi G. Circannual rhythm of plasmatic vitamin D levels and the association with markers of psychophysical stress in a cohort of Italian professional soccer players. Chronobiol Int 2017;34(4):471-479.
Sanchis-Gomar F, Alis R, Rampinini E, Bosio A, Romagnoli M, Lombardi G, Lippi G. Alpha-amylase serum levels in professional soccer players are not related with physical fitness. J Sports Med Phys Fitness 2017;57(3):214-218.
Lombardi G, Vernillo G, Sansoni V, Perego S, Barbuti A, Merati G, Schena F, Banfi G, La Torre A. Plasminogen activator inhibitor-1 as a marker of cardiovascular response in professional mountain ultra-marathon runners. Clin Chem Lab Med 2017;55(1):e7-e9.
Sanchis-Gomar F, Lopez Ramon M, Alis R, Garatachea N, Pareja-Galeano H, Santos Lozano A, Catalan P, Sansoni V, Perego S, Lombardi G, Loellgen H, Bueno H, Serrano-Ostariz E, Lucia A. No evidence of adverse cardiac remodeling in former elite endurance athletes. Int J Cardiol 2016;222:171-7.
Vernillo G, Agnello L, Barbuti A, Di Meco S, Lombardi G, Merati G, La Torre A. Postexercise Autonomic Function After Repeated-Sprints Training. Eur J Appl Physiol 2015;115(11):2445-55.
Alis R, Sanchis-Gomar F, Ferioli D, La Torre A, Bosio A, Xu J, Lombardi G, Romagnoli M, Rampini E. Association between physical fitness and mean platelet volume in professional soccer players. Clin Chem Lab Med 2015;53(10):e249-52.
Corsetti R, Perego S, Sansoni V, Xu, J, Barassi A, Banfi G, Lombardi G. Osteocartilaginous metabolic markers change over a 3-week stage race in pro-cyclists. Scand J Clin Lab Invest 2015;75:523-530.
Sanchis-Gomar F, Alis R, Rampinini E, Bosio A, Romagnoli M, Lombardi G, Lippi G. Hs-cTnT levels in professional soccer players throughout a season: No evidence of sustained cardiac damage. Int J Cardiol 2015;197:292-293.
Sanchis-Gomar F, Alis R, Rampinini E, Bosio A, Ferioli D, La Torre A, Xu J, Sansoni V, Perego S, Romagnoli M, Lombardi G. Adropin and apelin fluctuations throughout a season in professional soccer players: Are they related with performance? Peptides 2015;70:32-6.
Colombini A, Machado M, Lombardi G, Lanteri P, Banfi G. Modifications of biochemical parameters related to protein metabolism and renal function in male soccer players after a match. J Sports Med Phys Fitness 2014;54(5):658-64.
Galliera E, Lombardi G, Marazzi MG, Grasso D, Vianello E, Pozzoni R, Banfi G, Corsi Romanelli MM. Acute exercise in elite rugby players increases the circulating level of the cardiovascular biomarker GDF-15. Scand J Clin Lab Invest 2014;74(6):492-9.
Grasso D, Lanteri P, Di Bernardo C, Mauri C, Porcelli S, Colombini A, Zani V, Bonomi FG, Melegati G, Banfi G, Lombardi G. Salivary steroid hormones response to whole-body cryotherapy in elite rugby players. J Biol Regul Homeost Agents 2014;28(2):291-300.
Lombardi G, Colombini A, Porcelli S, Mauri C, Zani V, Bonomi F, Melegati G, Banfi G. Muscular damage and kidney function in rugby players after daily whole body cryostimulation. Physiol J 2014;790540.
Lombardi G, Lanteri P, Fiorella PL, Simonetto L, Impellizzeri FM, Bonifazi M, Banfi G, Locatelli M. Comparison of the Hematological Profile of Elite Road Cyclists during the 2010 and 2012 GiroBio Ten-Day Stage Races and Relationships with Final Ranking. PLoS ONE 2013;8(4):e63092.
Lombardi G, Banfi G, Lippi G, Sanchis-Gomar F. Ex-vivo erythrocyte generation and blood doping. Blood Transfus 2013;11:161-3.
Lombardi G. Reply to Gore C. et al.: Plasma volume shift during multiday racing. Clin Chem Lab Med 2013;30:1-2.
Lombardi G, Lanteri P, Porcelli S, Mauri C, Colombini A, Grasso D, Zani V, Bonomi FG, Melegati G, Banfi G. Hematological Profile and Martial Status in Rugby Players during Whole Body Cryostimulation. PLoS ONE 2013;8(2):e55803.
Colombini A, Corsetti R, Machado M, Graziani R, Lombardi G, Lanteri P, Banfi G. Serum Creatine Kinase Activity and Its Relationship With Renal Function Indices in Professional Cyclists During the Giro d’Italia 3-Week Stage Race. Clin J Sports Med 2012;22(5):408-13.
Corsetti R, Lombardi G, Barassi A, Lanteri P, Colombini A, MelziD’Eril G, Banfi G. Cardiac indexes, cardiac damage biomarkers and energy expenditure in professional cyclists during the Giro d’Italia 3-weeks stage race. Biochem Med 2012;22(2):237-46.
Corsetti R, Lombardi G, Lanteri P, Colombini A, Graziani R, Banfi G. Haematological and iron metabolism parameters in professional cyclists during the Giro d’Italia 3-weeks stage race. Clin Chem Lab Med 2012;50(5):949-56.
Colombini A, Lombardi G, Banfi G, Arpesella M, Pelissero G. Athleticogenomics and elite athletes: a review of the state of the art and a possible relationship with inflammatory response. It J Pub Health 2011;8(3):275-85.
Díaz V, Lombardi G, Ricci C, Jacobs RA, Montalvo Z, Lundby C, Banfi G Reticulocyte and haemoglobin profiles in elite triathletes over four consecutive seasons. Int J Lab Hematol 2011;33(6):638-44.
Lombardi G, Ricci C, Banfi G. Effects of winter swimming on haematological parameters. Biochem Med 2011;21(1):71-8.
Banfi G, Lombardi G, Colombini A, Melegati G. Whole body cryotherapy. Sports Med 2010;40:509-17.
Lombardi G, Colombini A, Ricci C, Freschi M, Lippi G, Banfi G. Serum uric acid in top-level alpine skiers over four consecutive competitive seasons. Clin Chim Acta 2010;411:645–8.
Experimental clinical chemistry
Ferrari D, Lombardi G, Banfi G. Concerning the vitamin D reference range: pre-analytical and analytical variability of vitamin D measurement. Biochem Med 2017;27(3):030501.
Lombardi G, Sansoni V, Banfi G. Measuring myokines with cardiovascular functions: pre-analytical variables affecting the analytical output. Ann Transl Med 2017;5(15).
Lombardi G, Barbaro M, Locatelli M, Banfi G. Novel bone metabolism-associated hormones: the importance of the pre-analytical phase for understanding their physiological roles. Endocrine 2017;56(3):460-484.
Lombardi G, Perego S, Sansoni V, Diani M, Banfi G, Altomare G. Anti-adalimumab antibodies in psoriasis: lack of clinical utility and laboratory evidences. BMJ Open 2016;6(12):e011941
Lombardi G, Perego S, Sansoni V, Banfi G. Circulating miRNA as fine regulators of the physiological responses to physical activity: pre-analytical warnings for a novel class of biomarkers. Clin Biochem 2016;49(2016):1331-9
Lombardi G, Banfi G. Effects of sample matrix and storage conditions on full-length visfatin measurement in blood. Clin Chim Acta 2015;440:140-2.
Lombardi G, Colombini A, Lanteri P, Banfi G. Reticulocytes in Sports Medicine. An update. Adv Clin Chem 2013;59:125-53.
Lanteri P, Lombardi G, Colombini A, Banfi G. Vitamin D in exercise: Physiologic and analytical concerns. Clin Chim Acta 2013;415:45-53.
Lanteri P, Lombardi G, Colombini A, Grasso D, Banfi G. Stability of osteopontin in plasma and serum. Clin Chem Lab Med 2012;50(11):1979–84.
Colombini A, Corsetti R, Graziani R, Lombardi G, Lanteri P, Banfi G. Evaluation of creatinine, cystatin C and eGFR by different equations in professional cyclists during the Giro d’Italia 3-weeks stage race. Scand J Clin Lab Invest 2012;72(2):114-20.
Milic R, ColombiniA, Lombardi G, Lanteri P, Banfi G. Estimation of glomerular filtration rate by MDRD equation in athletes: role of body surface area. Eur J Appl Physiol 2011;112(1):201-6.
Lombardi G, Lanteri P, Colombini A, Lippi G, Banfi G. Stability of Haematological Parameters and Its Relevance on the Athlete’s Biological Passport Model. Sports Med 2011;41(12):1033-42.
Banfi G, Lombardi G, Colombini A, Lippi G. Analytical variability in sport haematology: its importance in an antidoping setting. Clin Chem Lab Med 2011;49(5):779-82.
Banfi G, Lombardi G, Colombini A, Lippi G. A world apart. Inaccuracies of laboratory methodologies in antidoping testing. Clin Chim Acta 2010;411:1003-8.
Banfi G, Colombini A, Lombardi G. Indirect markers for detecting growth hormone abuse in athletes. Clin Endocrinol 2010;73(2):272-3.
Experimental Nutrition
Perego S, Sansoni V, Banfi G, Lombardi G. Sodium Butyrate counteracts the pro-inflammatory effects of TNFα in osteosarcoma cells: possible anti-proliferative, pro-differentiating, and immunomodulatory effects in osteoblasts. Int J Immunopathol Pharmacol [Epub Ahead of Print]
Colombini A, Perego S, Ardoino I, Marasco E, Lombardi G, Fiorilli A, Biganzoli E, Tettamanti G, Ferraretto A. Evaluation of a possible direct effect by casein phosphopeptides on paracellular and vitamin D controlled transcellular calcium transport mechanisms in intestinal human HT-29 and Caco2 cell lines. Food Funct 2013;4(8):1195-203.
Cosentino S, Donida BM, Marasco E, Del Favero E, Cantù L, Lombardi G, Colombini A, Iametti S, Valeperta S, Fiorilli A, Tettamenti G, Ferraretto A. Calcium ions enclosed in casein phosphopeptide aggregates are directly involved in the mineral uptake by differentiated HT-29 cells. Int Dairy J 2010;20:770-6.
Cosentino S, Gravaghi C, Donetti E, Donida BM, Lombardi G, Bedoni M, Fiorilli A, Tettamanti G, Ferraretto A. Caseinphosphopeptide-induced calcium uptake in human intestinal cell lines HT-29 and Caco2 is correlated to cellular differentiation. J Nutr Biochem 2010;21:247-54.
Ferraretto A, Gravaghi C, Donetti E, Bedoni M, Cosentino S, Donida BM, Lombardi G, Fiorilli A, Tettamanti G. Casein phosphopeptide-induced calcium uptake in intestinal cells is related to cell differentiation degree. Ann Nutr Metab 2007;51(S1):145-6.
Methodologies
Nason F, Morganti E, Collini C, Ress C, Bersini S, Pennati G, Boschetti F, Colombini A, Lombardi G, Banfi G, Lorenzelli L, Dubini G. Design of microfluidic devices for drug screening on in-vitro cells for osteoporosis therapies. Microelectr Eng 2011;88(8):1801-6.
Ferraretto A, Gravaghi C, Donetti E, Cosentino S, Donida BM, Bedoni M, Lombardi G, Fiorilli A, Tettamanti G. New methodological approach to induce a differentiation phenotype in Caco-2 cells prior to post confluence stage. Anticancer Res 2007;27:3919-26.