Bio
Paola De Luca received her Master degree in Biological Sciences, biomolecular address, in 2008 from Università degli Studi di Messina, Italy. She achieved the post-graduate second level Master in biotechnology from the Università della Calabria, Cosenza, Italy in 2011. From May 2011 to November 2012 she was a research fellow assistant at the Molecular Pharmacology laboratory in Oncology department of Mario Negri Institute, Milan, Italy. From November 2011 to November 2012 she was involved in a project concerning the bone metastasis in collaboration with Galeazzi Orthopaedic Institute, Milan. In 2016 she achieved the PhD at the Università degli Studi di Milano, in Clinical and Experimental Nutrition, School of Biochemical, Nutritional and Metabolic Sciences. She is a post-doc researcher in the Orthopaedic Biotechnology Lab of Galeazzi Orthopaedic Institute and she has expertise in cellular and molecular biology, experimental nutrition, molecular pharmacology in oncological field. She is taking part in research projects concerning the regenerative role of mesenchymal stem/stromal cells and the characterization of different tissue specific progenitors in musculoskeletal field.
Publications
Cauci S, Viganò M, de Girolamo L, De Luca P, Orfei CP, Banfi G, Lombardi G, Brayda-Bruno M, Colombini A. High levels of circulating type II collagen degradation marker (CTx-II) are associated with specific VDR polymorphisms in patients with adult vertebral osteochondrosis. International Journal of Molecular Sciences. 2017; 18 (10). doi:10.3390/ijms18102073
Brayda-Bruno M, Viganò M, Cauci S, Vitale JA, de Girolamo L, De Luc, P, Lombardi G, Banfi G, Colombini A. Plasma vitamin D and osteo-cartilaginous markers in Italian males affected by intervertebral disc degeneration: Focus on seasonal and pathological trend of type II collagen degradation. Clinica Chimica Acta. 2017; 471: 87-93.
De Luca P, Bruschi S, Maggioni M, Stuknytė M, Cattaneo S, Bottani M, Fiorilli A, Rossi F, De Noni I, Ferraretto A. Gastrointestinal digestates of Grana Padano and Trentingrana cheeses promote intestinal calcium uptake and extracellular bone matrix formation in vitro. Food Research International. 2016; 89: 820-827.
Maggioni M, Stuknytė M, De Luca P, Cattaneo S, Fiorilli A, De Noni I, Ferraretto A. Transport of wheat gluten exorphins A5 and C5 through an in vitro model of intestinal epithelium. Food Research International. 2016; 88 (Part B): 319-326.
Stuknyte, M., Maggioni, M., Cattaneo, S., De Luca, P., Fiorilli, A., Ferraretto, A., De Noni, I. Release of wheat gluten exorphins A5 and C5 during in vitro gastrointestinal digestion of bread and pasta and their absorption through an in vitro model of intestinal epithelium. Food Research International. 2015; 72: 208-214.
Perego S, Del Favero E, De Luca P, Dal Piaz, F, Fiorilli A, Cantù L, Ferraretto A. Calcium bioaccessibility and uptake by human intestinal like cells following in vitro digestion of casein phosphopeptide-calcium aggregates. Food and Function. 2015; 6(6): 1796-1807.
De Luca P, Arrigoni C, Gilardi M, Previdi S, Broggini M, Moretti M. Direct but not indirect co-culture with osteogenically differentiated human bone marrow stromal cells increases RANKL/OPG ratio in human breast cancer cells generating bone metastases. Molecular Cancer. 2014; 13(1): 1-6.